个人简介

       1986年4月生，山东青岛人。2008年获中国农业大学农学学士学位，师从张振贤教授；2011年获中国农业科学院研究生院农学硕士学位，2014年获中国农业科学院研究生院农学博士学位，师从方智远院士。2014年至今在中国农业科学院蔬菜花卉研究所甘蓝课题组工作。现为研究员、博士生导师、十字花科研究室副主任。兼任华中农业大学、沈阳农业大学、河北农业大学、广西大学、北京农学院等高校的研究生导师。

       主持国家自然科学基金项目2项，国家重点研发计划项目/课题2项。担任Front Plant Sci期刊副主编、Horticulturae、Veg Res等SCI期刊编委。获得神农中华农业科技奖、北京市农业技术推广奖等省部级奖励3项。2022年入选中国农业科学院“农科英才领军人才B类”。

科研情况

       主要从事甘蓝遗传育种及分子生物学相关研究。具体研究内容包括：甘蓝抗病、优异种质资源创新；甘蓝抗病抗逆鉴定、单倍体育种、分子标记辅助育种等技术的建立、完善与应用；甘蓝重要农艺性状基因的克隆与分子机制研究；甘蓝新品种选育与推广。重点研究方向为甘蓝显性不育、枯萎病抗性、黑腐病抗性等关键农艺性状基因的功能挖掘、分子机制解析及在育种中的应用。尤其是针对农业重大病害甘蓝枯萎病，历时13年开展了病原分化、抗源挖掘、基因克隆、标记开发、分子机制挖掘等系统性研究，建立了完整的抗枯萎病育种技术体系，首次克隆了甘蓝枯萎病抗性基因，育成的YR中甘21入选2022中国农业农村重大科技新成果，并在主产区大面积推广，为推动蔬菜学科发展、支撑蔬菜产业、民族种业和乡村振兴做出贡献。

       以第一或通讯作者在Nature Genetics、Nature Communications、Plant Biotechnology Journal、Horticulture Research等刊物发表SCI论文50余篇；参编著作2部；以第一完成人授权国家发明专利7项；以第一完成人育成和推广YR中甘21、中甘26、中甘28等甘蓝新品种10个，累计推广面积超200万亩。

主要成果

人才项目

1. 2019：中国农业科学院蔬菜花卉研究所“中蔬英才”

2. 2021：“国家高层次人才特殊支持计划”青年拔尖人才

3. 2022：中国农业科学院“农科英才领军人才”B类

科技奖励

1. 2016：“伟丽创新精英奖”三等奖

2. 2018：中国农业科学院成果转化贡献奖先进集体

3. 2019：神农中华农业科技奖优秀创新团队奖

4. 2019：北京市农业技术推广奖二等奖

5. 2019：中蔬英才所级青年英才

6. 2019：全国农业农村系统先进集体奖

7. 2019：中国农业科学院优秀创新团队

8. 2020：中国农业科学院成果转化优秀创新团队奖

 
论文著作

1. Li X#, Wang Y#, Cai C#, Ji J#, Han F#, Zhang L#, Chen S, Zhang L, Yang Y, Tang Q, Bucher J, Wang X, Yang L, Zhuang M, Zhang K*, Lv H^*, Bonnema G*, Zhang Y*, Cheng F*. Large-scale gene expression alterations introduced by structural variation drive morphotype diversification in Brassica oleracea. Nature genetics, 2024, https://doi.org/10.1038/s41588-024-01655-4.
   

2. Han F#, Yuan K#, Sun W#, Zhang X, Liu X, Zhao X, Yang L, Wang Y, Ji J, Liu Y, Li Z, Zhang J, Zhang C, Huang S, Zhang Y*, Fang Z*, Lv H^*. A natural mutation in the promoter of Ms-cd1 causes dominant male sterility in Brassica oleracea. Nature Communications, 2023, 14:6212.

3. Yuan K#, Zhao X#, Sun W, Yang L, Zhang Y, Wang Y, Ji J, Han F, Fang Z, Lv H^*. Map-based cloning and CRISPR/Cas9-based editing uncover BoNA1 as the causal gene for non-anthocyanin accumulation phenotype in curly kale (Brassica oleracea var. sabellica). Horticulture Research, 2023, uhad133.

4. Ji J#, Su H#, Cao W, Zhang X, Li H, Fang Z, Yang L, Zhang Y, Zhuang M, Wang Y, Vasiliy T, Lv H^*. Genetic analysis and mapping of QTLs for isolated microspore embryogenesis in cabbage. Scientia Horticulturae, 2023, 313:111897

5. Zhao X#, Yuan K#, Liu Y, Zhang N, Yang L, Zhang Y, Wang Y, Ji J, Fang Z, Han F*, Lv H^*. In vivo maternal haploid induction based on genome editing of DMP in Brassica oleracea. Plant Biotechnology Journal, 2022, DOI: 10.1111/pbi.13934

6. Zhu M, Yang L, Zhang Y, Zhuang M, Ji J, Hou X, Li Z, Han F, Fang Z, Lv H^*, Wang Y*. Introgression of clubroot resistant gene into Brassica oleracea L. from B. rapa based on homoeologous exchange. Horticulture Research, 2022, uhac195.

7. Wang Y#, Ji J#, Fang Z, Yang L, Zhuang M, Zhang Y*, Lv H^*. BoGDB: an integrative genomic database for Brassica oleracea L. Front Plant Sci. 2022, 13:852291.

8. Kong C#, Su H#, Deng S, Ji J, Wang Y, Zhang Y, Yang L, Fang Z, Lv H^*. Global DNA Methylation and mRNA miRNA Profiles Reveal Key Events Activated by Short term Heat Shock Boost Early Microspore Embryogenesis in Cabbage (Brassica oleracea). Int J Mol Sci. 2022, 23:5147.

9. Tong L#, Zhao C#, Liu J, Yang L, Zhuang M, Zhang Y, Wang Y, Ji J, Kuang B, Tang K, Fang Z, Fujimoto R*, Lv H^*. Resource Screening and Inheritance Analysis of Fusarium oxysporum sp. conglutinans Race 2 Resistance in Cabbage. Genes, 2022, 13:1590.

10. Li X#, Lv H^# , Zhang B, Fang Z, Yang L, Zhuang M, Liu Y, Li Z, Wang Y, and Zhang Y*. Dissection of Two QTL Clusters Underlying the Yield-related Heterosis in the Cabbage Founder Parent 01-20. Horticultural Plant J, 2022

11. Ji J#, Cao W#, Tong L, Fang Z, Zhang Y, Zhuang M, Wang Y, Yang L*, Lv H^*. Identification and validation of an ECERIFERUM2-LIKE gene controlling cuticular wax biosynthesis in cabbage (Brassica oleracea L. var. capitata L.). Theor Appl Genet. 2021.

12. Xiao Z, Liu X, Fang Z, Yang L, ZhangY, Wang Y, Zhuang M*, Lv H^*. Transcriptome and plant hormone analyses provide new insight into the molecular regulatory networks underlying hybrid lethality in cabbage (Brassica oleracea). Planta, 2021, 253:96.

13. Kong C, Chen G, Yang L, Zhuang M, Zhang Y, Wang Y, Ji J, Fang Z*, Lv H^*. Germplasm screening and inheritance analysis of resistance to black rot in a worldwide collection of cabbage (Brassica oleracea var. capitata) resources. Scientia Horticulturae, 2021

14. Xiao Z, Kong C, Han F, Yang L, Zhuang M, Zhang Y, Wang Y, Ji J, Li Z, Fang Z*, Lv H^*. Two user-friendly molecular markers developed for the identification of hybrid lethality genes in Brassica oleracea. Agronomy, 2021, 11:982.

15. Wang Y#, Ji J#, Tong L, Fang Z, Yang L, Zhuang M, Zhang Y*, Lv H^*. Global survey of the full-length cabbage transcriptome (Brassica oleracea var. capitata L.) reveals key alternative splicing events involved in growth and disease response. Int J Mol Sci. 2021, 22:10443.

16. Han F#, Zhang X#, Yang L, Zhuang M, Zhang Y, Liu Y, Li Z, Wang Y, Fang Z, Ji J, Lv H^*. Genome-wide characterization and analysis of the anthocyanin biosynthetic genes in Brassica oleracea. Planta. 2021.

17. Liu X#, Zhao C#, Yang Y, Zhang Y, Wang Y, Fang Z*, Lv H^*. Genome-wide identification, expression profile of the TIFY gene family in Brassica oleracea var. capitata and their divergent response to various pathogen infections and phytohormone treatments. Genes, 2020, 11:127.

18. Lv H^*, Fang Z, Yang L, Zhang Y, Wang Y. An update on the arsenal: mining resistance genes for disease management of Brassica crops in the genomic era. Hortic Res, 2020, 7:34.

19. Liu X#, Zhao C#, Yang L, Zhuang M, Zhang Y, Wang Y, Fang Z, Lv H^*. A time-resolved dual transcriptome analysis reveals the molecular regulating network underlying the compatible/incompatible interactions between cabbage (Brassica oleracea) and Fusarium oxysporum f. sp. conglutinans. Plant soil, 2020, 448:455-478.

20. Su H#, Chen G#, Yang L, Zhang Y, Wang Y, Fang Z*, Lv H^*. Proteomic variations after short-term heat shock treatment reveal differentially expressed proteins involved in early microspore embryogenesis in cabbage (Brassica oleracea) . PeerJ, 2020, 8:e8897

21. Lv H^#, Wang Y#, Han F#, Ji J#, Fang Z, Zhuang M, Li Z, Zhang Y*, Yang L*. A highquality reference genome for cabbage obtained with SMRT reveals novel genomic features and evolutionary characteristics. Sci Rep. 2020, 10:12394

22. Xiao Z, Xing M, Liu X, Fang Z, Yang L, ZhangY, Wang Y, Zhuang M*,Lv H^*. An efficient virus-induced gene silencing (VIGS) system for functional genomics in Brassicas using a cabbage leaf curl virus (CaLCuV)-based vector. Planta. 2020.

23. Xiao Z#, Han F#, Hu Y, Xue Y, Fang Z, Yang L, Zhang Y, Liu Y, Li Z, Wang Y, Zhuang M*, Lv H^*. 2019. Overcoming cabbage crossing-incompatibility by development and application of self-compatibility-QTLs specific makers and genome-wide background analysis. Front Plant Sci. 2019, 10:189

24. Su H, Xing M, Liu X, Fang Z, Yang L, Zhuang M, Zhang Y, Wang Y, Lv H^*. Genome-wide analysis of HSP70 family genes in cabbage (Brassica oleracea var. capitata) reveals their involvement in floral development. BMC genomics. 2019, 20:369.

25. Li G#, Lv H^#, Zhang S, Zhang S, Li F, Zhang H, Qian W, Fang Z*, Sun R*. TuMV Management for Brassica Crops through Host Resistance: Retrospect and Prospects. Plant Pathol. 2019, 68:1035–1044

26. Han F, Zhang X, Yuan K, Fang Z, Yang L, Zhuang M, Zhang Y, Wang Y, Liu Y, Li Z, Lv H^*. A user-friendly KASP molecular marker developed for the DGMS-based breeding system in Brassica oleracea species. Mol breeding. 2019, 39:90

27. Liu X#, Xing M#, Kong C, Fang Z, Yang L, Zhang Y, Wang Y, Ling J, Yang Y*, Lv H^*. Genetic diversity, virulence and race profiling of the Fusarium oxysporum f. sp. conglutinans strains affecting cabbages in China and comparison with other worldwide strains. Front Microbiol. 2019, 10:1373.

28. Kong C, de Passo V, Fang Z, Yang L, Zhuang M, Zhang Y, Wang Y, Vicente J*, Lv H^*. Complete Genome Sequence for strain 3811, race 1 of Xanthomonas campestris pv. campestris, the Causal Agent of Black Rot of Cruciferous Vegetables. Mol Plant Microbe In. 2019.

29. Xing M#, Su H#, Liu X, Yang L, Zhang Y, Wang Y, Fang Z*, Lv H^*. Morphological, transcriptomics, and phytohormone analysis shed light on the development of a novel dwarf mutant of cabbage (Brassica oleracea). Plant Sci. 2020. 290:110283

30. Liu X, Fang Z, Yang L, Zhang Y, Lv H^*. First Report of Brussels Sprouts and Broccoli Yellows Caused by Fusarium oxysporum in China. Plant Dis. 2018, 5

31. Han F#, Yuan K#, Kong C, Zhang X, Yang L, Zhuang M, Zhang Y, Li Z, Wang Y, Fang Z*, Lv H^*. Fine mapping and candidate gene identifcation of the genic malesterile gene ms3 in cabbage 51S. Theor Appl Genet. 2018, 131:2651–2661

32. Han F, Zhang X, Fang Z, Yang L, Zhuang M, Zhang Y, Li Z, Lv H^*. iTRAQ-Based Proteomic Analysis of Ogura-CMS Cabbage and Its Maintainer Line. Int J Mol Sci. 2018, 19:3180.

33. Lv H^*, Wang Q#, Han F, Liu X, Fang Z, Yang L, Zhuang M, Liu Y, Li Z, Zhang Y*. Genome-wide indel/SSR scanning reveals significant loci associated with excellent agronomic traits of a cabbage (Brassica oleracea) elite parental line ‘01-20’. Scientific Reports. 2017,7:41696

34. Liu X#, Han F#, Kong C, Fang Z, Yang L, Zhang Y, Zhuang M, Liu Y, Li Z, Lv H^*.Rapid introgression of the Fusarium wilt resistance gene into an elite cabbage line through the combined application of a microspore culture, genome background analysis, and disease resistance-specific marker assisted foreground selection. Front Plant Sci. 2017, 8:354

35. 34.Xiao Z#, Hu Y, Zhang X, Xue Y, Fang Z, Yang L, Zhang Y, Liu Y, Li Z, Liu X, Liu Z, Lv H^*, Zhuang M*. Fine Mapping and Transcriptome Analysis Reveal Candidate Genes Associated with Hybrid Lethality in Cabbage (Brassica oleracea). Genes. 2017,5;8(6).

36. Han F#, Zhang X#, Liu X, Su H, Kong C, Fang Z, Yang L, Zhuang M, Zhang Y, Liu Y, Li Z, Lv H^*. Comparative Analysis of Genome Wide DNA Methylation Profiles for the Genic Male Sterile Cabbage Line 01-20S and Its Maintainer Line. Genes. 2017, 5:8(6).

37. Lv H^#, Wang Q#, Liu X, Han F, Fang Z, Yang L, Zhuang M, Liu Y, Li Z, Zhang Y*. Whole-genome mapping reveals novel QTL clusters associated with main agronomic traits of cabbage (Brassica oleracea var. capitata L.). Front Plant Sci. 2016; 7: 989.

38. Lv H, Yang L, Kang J, Wang Q, Wang X, Fang Z, Liu Y, Zhuang M, Zhang Y, Lin Y, Yang Y, Xie B, Liu B, Liu J. Development of InDel markers linked to Fusarium wilt resistance in cabbage. Mol Breeding. 2013, 32:961-967

39. Lv H, Yang L, Kang J, Wang Q, Wang X, Fang Z, Liu Y, Zhuang M, Zhang Y, Lin Y, Yang Y, Xie B, Liu B, Liu J. Linkage map construction using InDel and SSR markers and QTL analysis of heading traits in cabbage. Mol Breeding. 2014, 34:87-98

40. Lv H, Fang Z, Yang L, Zhang Y, Wang Q, Liu Y, Zhuang M, Yang Y, Xie B, Liu B, Liu J, Kang J*, Wang X*. Mapping and analysis of a novel candidate Fusarium wilt resistance gene FOC1 in Brassica oleracea. BMC genomics. 2014, 15:1094

 

参编著作

1. Kole C. 2020. Genomic Designing of Climate-Smart Vegetable Crops. Springer Nature, Switzerland. 

2. 方智远. 2024. 中国结球甘蓝. 中国农业出版社.

 

授权专利（第一完成人）

1. 用于甘蓝枯萎病抗性筛选的PCR引物、试剂盒及其应用（ZL201610228387.5）

2. 用于甘蓝自交亲和性材料筛选的PCR引物、试剂盒及其应用（ZL201910401144.0）

3. 与甘蓝显性核基因雄性不育性相关的PCR标记及其应用（ZL201910334990.5）

4. 用于甘蓝黑腐病抗性筛选的PCR引物、试剂盒及其应用（ZL202010708098.1）

5. 鉴定或筛选甘蓝杂种致死亲本类型1的PCR引物组及应用（ZL202110189737.2）

6. 鉴定或筛选甘蓝杂种致死亲本类型2的PCR引物组及应用（ZL202110195225.7）

7. 甘蓝BoDMP9基因及其在母本单倍体诱导中的应用（ZL202211343602.8）

 

育成品种（第一完成人）

1. YR中甘21：GPD结球甘蓝（2021）110050

2. 中甘26：GPD结球甘蓝（2021）110090

3. 中甘27：GPD结球甘蓝（2021）110051

4. 中甘28：GPD结球甘蓝（2021）110074

5. 中甘166：GPD结球甘蓝（2022）110055

6. 中甘167：GPD结球甘蓝（2022）110057

7. 中甘35：GPD结球甘蓝（2022）110056

8. YR中甘15：GPD结球甘蓝（2022）110058

科研项目(近五年)

1. 主持：国家重点研发计划项目（2023YFE0111400）：2023.10-2025.9

2. 主持：国家重点研发计划课题（2023YFD1200005）：2023.11-2028.10

3. 主持：国家自然科学基金面上项目（32072570）：2021.1-2024.12

4. 主持：国家自然科学基金青年项目（31701927），2018.1-2020.12

5. 主持：中央级公益性科研院所基本科研业务费专项（Y2020PT01），2020.1-2020.12

6. 主持：国家重点研发计划项目子课题（2016YFD0100204-11），2016.7-2020.12

7. 主持：蔬菜种质创新国家重点实验室项目（201902），2019.7-2021.6

 

写给考生的话：

道阻且长，行则将至；行而不辍，未来可期。